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中文名稱： 兔抗PATE3多克隆抗體
英文名稱： Anti-PATE3 rabbit polyclonal antibody
別 名： HEL-127; PATE-DJ
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： PATE3
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
|
WB Predicted band size: |
12 kDa |
|
WB Positive control: |
HeLa cells |
|
WB Recommended dilution: |
500-2000 |
|
SwissProt: |
B3GLJ2 |
|
Synonyms： |
HEL-127; PATE-DJ |
|
Full name: |
prostate and testis expressed 3 |
|
Immunogen: |
Fusion protein of human PATE3 |
|
Name of antibody: |
PATE3 |
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Applications: |
WB |
|
Background: |
PATE3 (prostate and testis expressed protein 3), also known as PATE-DJ or HEL-127, is a 98 amino acid protein that contains one UPAR/Ly6 domain and belongs to the PATE family. PATE3 is a secreted protein that is expressed in prostate and testis. The gene that encodes PATE3 consists of around 3,490 bases and maps to human chromosome 11p15.5. Chromosome 11, which comprises approximately 4% of the human genome, is considered a gene and disease association-dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes. |
