Name: VPS37A 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱(chēng)： VPS37A 抗原（重組蛋白）

英文名稱(chēng)： VPS37A Antigen (Recombinant Protein)

別名： VPS37A subunit of ESCRT-I; HCRP1; PQBP2; SPG53

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類(lèi)別：抗原

概述

Fusion protein corresponding to C terminal 174 amino acids of human VPS37A

技術(shù)規(guī)格

Full name:	VPS37A subunit of ESCRT-I
Synonyms:	HCRP1; PQBP2; SPG53
Swissprot:	Q8NEZ2
Gene Accession:	BC022363
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.

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