Name: EIF2AK3抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： EIF2AK3抗原（重組蛋白）

英文名稱： EIF2AK3 Antigen (Recombinant Protein)

別名： PEK; WRS; PERK

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to a region derived from 867-1116 amino acids of human EIF2AK3

技術(shù)規(guī)格

Full name:	eukaryotic translation initiation factor 2 alpha kinase 3
Synonyms:	PEK; WRS; PERK
Swissprot:	Q9NZJ5
Gene Accession:	BC126354
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

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