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中文名稱：BCL2L12抗原（重組蛋白）

英文名稱：BCL2L12 Antigen (Recombinant Protein)

儲      存：冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to a region derived from N terminal 333 amino acids of human BCL2L12


技術規(guī)格

Full name:

BCL2-like 12 (proline rich)

Swissprot:

Q9HB09

Gene Accession:

BC104005

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants


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