中文名稱：CDKN1A抗原（重組蛋白）

英文名稱：CDKN1A Antigen (Recombinant Protein)

儲存：冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to a region derived from 5-164 amino acids of human CDKN1A

技術(shù)規(guī)格

Full name:

cyclin dependent kinase inhibitor 1A

Synonyms:

P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1

Swissprot:

P38936

Gene Accession:

BC000275

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of apoptosis following caspase activation. Mice that lack this gene have the ability to regenerate damaged or missing tissue. Multiple alternatively spliced variants have been found for this gene.

展開全部

CDKN1A抗原（重組蛋白）說明書
下載

6080yyy午夜理论av片,黄片aaawww,国产色婷婷激情片,久久午夜国产精品,久久色av网址导航,销魂美女做爰免费视频,日韩黄色三级电影在线观看,在线电影人妻在线观看,日本高清成人片www网站免费,长途公共汽车上的轮杆

021-54845833/15800441009

ELISA試劑盒

PCR試劑盒

生化試劑盒

細胞系

細胞庫

基礎(chǔ)培養(yǎng)基

完全培養(yǎng)基

原代細胞

細胞專用培養(yǎng)基

菌株

生化試劑

病理染色液

科研抗體

標準品

血清

形態(tài)病理檢測

分子病理

超微病理

產(chǎn)品中心

最新產(chǎn)品

相關(guān)文章

CDKN1A抗原（重組蛋白）

Full name:	cyclin dependent kinase inhibitor 1A
Synonyms:	P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1
Swissprot:	P38936
Gene Accession:	BC000275
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of apoptosis following caspase activation. Mice that lack this gene have the ability to regenerate damaged or missing tissue. Multiple alternatively spliced variants have been found for this gene.