技術(shù)規(guī)格
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Background: |
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
KEAP1 |
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Immunogen: |
Synthetic peptide of human KEAP1 |
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Full name: |
kelch-like ECH-associated protein 1 |
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Synonyms: |
INrf2; KLHL19 |
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SwissProt: |
Q14145 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer and Human esophagus cancer |
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IHC Recommend dilution: |
25-100 |


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