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中文名稱： GHSR 抗原

英文名稱：GHSR Antigen

相關(guān)類別：抗原

儲      存：冷凍（-20℃）

概述

Synthetic peptide corresponding to a region derived from 18-32 amino acids of human growth hormone secretagogue receptor


技術(shù)規(guī)格

Full name

growth hormone secretagogue receptor

Swissprot

Q92847

Gene Accession

NP_004113

Background

This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.

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