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  • MCM6抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW16828
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：40
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中文名稱： MCM6抗原（重組蛋白）

英文名稱： MCM6 Antigen (Recombinant Protein)

別       名： Mis5; P105MCM; MCG40308

儲       存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述

Fusion protein corresponding to C terminal 300 amino acids of human MCM6

技術(shù)規(guī)格

Full name:

minichromosome maintenance complex component 6

Synonyms:

Mis5; P105MCM; MCG40308

Swissprot:

Q14566

Gene Accession:

BC032374

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.