Name: NFKBIA抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： NFKBIA抗原（重組蛋白）

英文名稱： NFKBIA Antigen (Recombinant Protein)

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to a region derived from 1-317 amino acids of human NFKBIA

技術(shù)規(guī)格

Full name:	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
Synonyms:	IKBA; MAD-3; NFKBI
Swissprot:	P25963
Gene Accession:	BC004983
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

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