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  • ITGB3BP抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW18054
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:90
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中文名稱:ITGB3BP抗原(重組蛋白)

英文名稱 ITGB3BP Antigen (Recombinant Protein)

別      名: CENPR, NRIF3, TAP20, CENP-R, HSU37139

儲      存: 冷凍(-20℃)

相關(guān)類別 抗原

概述

Fusion protein corresponding to a region derived from 41-177 amino acids of human ITGB3BP


技術(shù)規(guī)格

Full name:

integrin beta 3 binding protein (beta3-endonexin)

Synonyms:

CENPR, NRIF3, TAP20, CENP-R, HSU37139

Swissprot:

Q13352

Gene Accession:

BC014385

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.