Name: NRP1抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： NRP1抗原（重組蛋白）

英文名稱： NRP1 Antigen (Recombinant Protein)

別名： NP1, NRP, BDCA4, CD304, VEGF165R

儲存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to a region derived from 310-609 amino acids of human NRP1

技術(shù)規(guī)格

Full name:	neuropilin 1
Synonyms:	NP1, NRP, BDCA4, CD304, VEGF165R
Swissprot:	O14786
Gene Accession:	BC007737
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

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